Covid-19 Pubmed Articles

Covid-19 Pubmed Articles 
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» Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
08/04/25 20:00 from sars-cov-2 spike protein
Melissa officinalis is a perennial medicinal plant traditionally used for its diverse biological activities, including antiviral properties. This study investigates the antiviral efficacy of various extracts, including water, acetone, al...

» Cardiac symptoms in patients 3-6 months after contracting COVID-19- data from the polish STOP-COVID registry
08/04/25 20:00 from covid-19
CONCLUSION: Cardiological symptoms are common among health issues that patients must face after contracting COVID-19. People with palpitations had more excessive ventricular extrasystoles than patients without these symptoms.

» The cost of delivering COVID-19 vaccines in Mozambique: a bottom-up costing study
08/04/25 20:00 from covid-19
CONCLUSIONS: The cost of delivering COVID-19 vaccines in Mozambique was found to be low compared to other countries, due to heavy reliance on existing resources and little additional investment into the program. Findings from this study ...

» The impact of insulin requirement on mortality and morbidity in non-diabetic covid-19 patients in the intensive care unit: A retrospective, observational study
08/04/25 20:00 from covid-19
CONCLUSIONS: Insulin requirement in non-diabetic COVID-19 ICU patients is a predictor of 6-month mortality. High-dose corticosteroids exacerbate glycemic dysregulation, increasing insulin needs. SARS-CoV-2-induced beta-cell damage and hy...

» Altered Circulating Cytokine Profile Among mRNA-Vaccinated Young Adults: A Year-Long Follow-Up Study
08/04/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: The findings of this study indicated that COVID-19 vaccination resulted in an increase in cytokine levels, which signifies the persistence of the humoral immune response to messenger RNA (mRNA) vaccines. This effect may be a...

» Online extended focused assessment with sonography for trauma (EFAST) course enhanced knowledge and perceived confidence among medical trainees during the COVID-19 pandemic disaster
08/04/25 20:00 from covid-19
CONCLUSION: The online EFAST course enhanced participants' knowledge and perceived confidence, demonstrating the potential of online clinical education during global crises.

» "There's a lot of unknowns": a thematic analysis of the experiences of young adults with cancer who died during a psychosocial intervention trial
08/04/25 20:00 from covid-19
CONCLUSIONS: YAs who approached end-of-life or saw unexpectedly fast declines in their healthcare trajectory showed many similarities to YAs outside of end-of-life contexts. Some, but not all, participants reflected on goals and challeng...

» Cross-variant immune shield: computational multiepitope vaccine design against B.617.2 to Omicron sub-lineages in SARS-CoV-2
08/04/25 20:00 from sars-cov-2 spike protein
The COVID-19 pandemic had a profound impact on global health. This study focuses on an in-depth analysis of the structural proteins (Spike (S), Nucleocapsid (N), Membrane (M), and Envelope (E) protein) of SARS-CoV-2 and its variants, aim...

» Clinical impact of concurrent autologous adoptive T cells immunotherapy in active COVID-19 infected cancer patients for chemotherapy
08/04/25 20:00 from covid-19
CONCLUSIONS: These data demonstrate the clinical safety profiles while ACT infusions with active COVID-19 infection.The intervention of ACT for cancer patients could generate the benefit for symptom alleviation with improved recovery tim...

» Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania
08/04/25 20:00 from Coronavirus origins
CONCLUSION: This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing ...

» Post COVID-19 among young adults- prevalence and associations with general health, stress, and lifestyle factors
08/04/25 20:00 from covid-19
CONCLUSIONS: Almost 4% of young adults with previous self-reported COVID-19 had ongoing symptoms of PCC three years after the onset of the pandemic. This group reported poorer health and more adverse changes in lifestyle factors than par...

» Cardiac symptoms in patients 3-6 months after contracting COVID-19- data from the polish STOP-COVID registry
08/04/25 20:00 from sars-cov-2
CONCLUSION: Cardiological symptoms are common among health issues that patients must face after contracting COVID-19. People with palpitations had more excessive ventricular extrasystoles than patients without these symptoms.

» The effect of COVID vaccination timing on the seroprevalence of IgG antibodies: evidence from the Guayas region of Ecuador
08/04/25 20:00 from sars-cov-2 spike protein
CONCLUSION: The results suggest that a significant portion of the study population was already infected with SARS-CoV-2 prior to the vaccination. As expected, seropositivity increased alongside vaccination efforts. We determined that Pfi...

» Enhancing accessibility and equity in utilization of virtual care: Virtual Care @ Your Library pilot project
08/04/25 20:00 from covid-19
CONCLUSIONS: The VC@YL initiative demonstrated how community-based programs can effectively enhance access to virtual care, particularly for individuals facing technological barriers. This pilot project showed strong potential for improv...

» Online Racial Discrimination and College Student Mental Health: Social Support as a Moderator
08/04/25 20:00 from covid-19
Many college students experience racism and discrimination, which negatively impacts their mental health. As COVID-19 has brought about increased reliance on virtual spaces, increased online racial discrimination (ORD) has also become a ...

» Perspectives on COVID-19 Vaccination Among Unvaccinated and Under-Vaccinated African American/Black and Latine Frontline Essential Workers: A Qualitative Exploration
08/04/25 20:00 from covid-19
Racial/ethnic disparities in COVID-19 morbidity and mortality are serious in the United States, particularly among African American/Black and Latine (AABL) populations. Staying up-to-date on COVID-19 vaccination is essential for mitigati...

» Evaluating the Effects of the COVID-19 Pandemic on HIV Testing, Enrollment, ART Use and Mortality in Suriname Using Interrupted Time Series Analysis
08/04/25 20:00 from covid-19
Our study evaluates the changes in HIV testing, new enrollments in the HIV surveillance system, treatment, and mortality of people with HIV during and after the SARS-CoV-2 (COVID-19) pandemic in Suriname. A retrospective population-based...

» Expert consensus on implementing patient-reported outcomes in telehealth: findings from an international Delphi study
08/04/25 20:00 from covid-19
CONCLUSION: The expert consensus achieved provides important insights from an international perspective on how PROs are currently used via telehealth and the needed implementation support to advance their expansion in research and practi...

» The Relationship Between Spiritual Well-Being and Fear of COVID-19 Among Cancer Patients in Turkey
08/04/25 20:00 from covid-19
This study focuses on the relationship between the faith sub-dimension of spiritual well-being and COVID-19-related fear among cancer patients. The research employs a descriptive, correlational, and cross-sectional approach to understand...

» The impact of insulin requirement on mortality and morbidity in non-diabetic covid-19 patients in the intensive care unit: A retrospective, observational study
08/04/25 20:00 from sars-cov-2
CONCLUSIONS: Insulin requirement in non-diabetic COVID-19 ICU patients is a predictor of 6-month mortality. High-dose corticosteroids exacerbate glycemic dysregulation, increasing insulin needs. SARS-CoV-2-induced beta-cell damage and hy...

» Optimal Timing of Vaccination: A Narrative Review of Integrating Strategies for COVID-19, Influenza, and Respiratory Syncytial Virus
08/04/25 20:00 from covid-19
Lower respiratory tract infections caused by SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) cause a significant disease burden globally, despite the availability of effective vaccines. Certain populations, such as older adu...

» Perspectives on COVID-19 Vaccination Among Unvaccinated and Under-Vaccinated African American/Black and Latine Frontline Essential Workers: A Qualitative Exploration
08/04/25 20:00 from sars-cov-2
Racial/ethnic disparities in COVID-19 morbidity and mortality are serious in the United States, particularly among African American/Black and Latine (AABL) populations. Staying up-to-date on COVID-19 vaccination is essential for mitigati...

» Global Profiles of Positive Youth Development: A Person-Oriented Analysis among Emerging Adults Living in 21 Countries
08/04/25 20:00 from covid-19
Although global research on the 5Cs model of Positive Youth Development (PYD; competence, confidence, connection, character, and caring) has expanded in recent years, there is a lack of understanding about distinct and consistent PYD pro...

» Evaluating the Effects of the COVID-19 Pandemic on HIV Testing, Enrollment, ART Use and Mortality in Suriname Using Interrupted Time Series Analysis
08/04/25 20:00 from sars-cov-2
Our study evaluates the changes in HIV testing, new enrollments in the HIV surveillance system, treatment, and mortality of people with HIV during and after the SARS-CoV-2 (COVID-19) pandemic in Suriname. A retrospective population-based...

» Optimal Timing of Vaccination: A Narrative Review of Integrating Strategies for COVID-19, Influenza, and Respiratory Syncytial Virus
08/04/25 20:00 from sars-cov-2
Lower respiratory tract infections caused by SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) cause a significant disease burden globally, despite the availability of effective vaccines. Certain populations, such as older adu...

» The Relationship Between Spiritual Well-Being and Fear of COVID-19 Among Cancer Patients in Turkey
08/04/25 20:00 from coronavirus
This study focuses on the relationship between the faith sub-dimension of spiritual well-being and COVID-19-related fear among cancer patients. The research employs a descriptive, correlational, and cross-sectional approach to understand...

» Emerging Viral Infections (ZIKV, SARS-CoV-2, and MPXV) and Depression: Ketamine and (S, R)-Ketamine as Promising Antidepressants
08/04/25 20:00 from sars-cov-2
Emerging viral pathogens, newly reported or rapidly evolving viruses, are a significant public health concern worldwide. Beyond their characteristic clinical presentations, emerging viruses, such as monkeypox virus (MPXV) and severe acut...

» Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
08/04/25 20:00 from sars-cov-2
Melissa officinalis is a perennial medicinal plant traditionally used for its diverse biological activities, including antiviral properties. This study investigates the antiviral efficacy of various extracts, including water, acetone, al...

» Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania
08/04/25 20:00 from Sars-Cov-2 origins
CONCLUSION: This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing ...

» Psychological distress in health care workers during the beginning, the middle, and the last part of the COVID-19 pandemic
08/04/25 20:00 from sars-cov-2
The COVID-19 pandemic placed significant psychological strain on healthcare workers. Our study tracked health care workers in the Czech Republic throughout the pandemic to examine the impact of stressors on psychological distress over ti...

» SnO₂NPs as a Nontoxic Antiviral Agent for Designing Protective Masks against Human Coronavirus Infection
08/04/25 20:00 from sars-cov-2
The COVID-19 pandemic has created a need to develop protective textiles that reduce the infection of SARS-CoV-2, mainly via face masks. The key issue in designing protective textiles is the functionalization with antiviral agents. This r...

» Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats
08/04/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
It is believed that bats, a natural reservoir host of coronaviruses (CoVs), may coexist with virus for long-term without showing symptoms of diseases. However, this description is mainly from observation on wild-captured bats, but withou...

» Effectiveness of full mRNA vaccinations to prevent COVID-19 among immunocompromised patients receiving tixagevimab-cilgavimab as pre-exposure prophylaxis
08/04/25 20:00 from sars-cov-2
Pre-exposure prophylaxis with monoclonal antibodies (mAbs) offers protection against COVID-19 in immunocompromised patients. To attest full vaccinations, defined by ≥ 3-dose mRNA vaccines, providing additional protection effect on mAbs a...

» Emerging Viral Infections (ZIKV, SARS-CoV-2, and MPXV) and Depression: Ketamine and (S, R)-Ketamine as Promising Antidepressants
08/04/25 20:00 from coronavirus
Emerging viral pathogens, newly reported or rapidly evolving viruses, are a significant public health concern worldwide. Beyond their characteristic clinical presentations, emerging viruses, such as monkeypox virus (MPXV) and severe acut...

» Impact of pre-Omicron COVID-19 vaccine boosters on the risk of Omicron variant infections: A systematic review and meta-regression
08/04/25 20:00 from sars-cov-2
CONCLUSION: Our findings refute the immune imprinting hypothesis that COVID-19 boosters impair immunity against new SARS-CoV-2 variants and support current recommendations to stay protected through updated booster vaccination once or twi...

» Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal (UNIVERSAL) study: a prospective observational cohort study protocol
08/04/25 20:00 from sars-cov-2
BACKGROUND: Respiratory viral infections (RVIs) are a significant cause of morbidity and hospital admission worldwide. However, the management of most viral infection-associated diseases remains primarily supportive. The recent COVID-19 ...

» Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
08/04/25 20:00 from coronavirus
Melissa officinalis is a perennial medicinal plant traditionally used for its diverse biological activities, including antiviral properties. This study investigates the antiviral efficacy of various extracts, including water, acetone, al...

» Safety Data for Baricitinib Use in Children With Severe SARS-CoV-2 Infection
08/04/25 20:00 from sars-cov-2
CONCLUSIONS: Baricitinib appears safe in children hospitalized for severe COVID-19. Most early baricitinib discontinuation for abnormal laboratory studies was secondary to provider caution.

» Psychological distress in health care workers during the beginning, the middle, and the last part of the COVID-19 pandemic
08/04/25 20:00 from coronavirus
The COVID-19 pandemic placed significant psychological strain on healthcare workers. Our study tracked health care workers in the Czech Republic throughout the pandemic to examine the impact of stressors on psychological distress over ti...

» Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania
08/04/25 20:00 from Covid-19 origins
CONCLUSION: This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing ...

» SnO(2)NPs as a Nontoxic Antiviral Agent for Designing Protective Masks against Human Coronavirus Infection
08/04/25 20:00 from coronavirus
The COVID-19 pandemic has created a need to develop protective textiles that reduce the infection of SARS-CoV-2, mainly via face masks. The key issue in designing protective textiles is the functionalization with antiviral agents. This r...

» Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats
08/04/25 20:00 from sars-cov-2
It is believed that bats, a natural reservoir host of coronaviruses (CoVs), may coexist with virus for long-term without showing symptoms of diseases. However, this description is mainly from observation on wild-captured bats, but withou...

» Respiratory Syncytial Virus hospitalisation burden in children below 18 years in six European countries (2016-2023) pre- and post-COVID-19 pandemic
08/04/25 20:00 from sars-cov-2
CONCLUSION: Hospital RSV burden in children is significant but currently not fully monitorable. Further efforts to harmonise coding practices both within and across countries would improve the quality of future analyses. Additional data ...

» Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal (UNIVERSAL) study: a prospective observational cohort study protocol
08/04/25 20:00 from coronavirus
BACKGROUND: Respiratory viral infections (RVIs) are a significant cause of morbidity and hospital admission worldwide. However, the management of most viral infection-associated diseases remains primarily supportive. The recent COVID-19 ...

» Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats
08/04/25 20:00 from coronavirus
It is believed that bats, a natural reservoir host of coronaviruses (CoVs), may coexist with virus for long-term without showing symptoms of diseases. However, this description is mainly from observation on wild-captured bats, but withou...

» Age-Specific Seroprevalence of Measles, Mumps, and Rubella IgG across All Age Groups in Chonburi Province, Thailand after the Coronavirus Disease 2019 Pandemic
08/04/25 20:00 from coronavirus
Thailand's Expanded Program on Immunization revised the timing of the second measles, mumps, and rubella (MMR) vaccine dose to 2.5 years in 2014 and later to 1.5 years in 2020. These adjustments can temporarily reduce vaccine coverage as...

» Boosting virus enrichment with macroporous magnetic sorbent based on ketoenamine covalent organic framework
08/04/25 20:00 from coronavirus
Effective surveillance and discovery of emerging and reemerging infectious viruses are crucial for predicting and controlling epidemic outbreaks. However, these efforts are significantly hindered by the low-titer existence of genetically...

» Enumerating the State and Local Public Health Workforce During the COVID-19 Response
08/04/25 20:00 from coronavirus
Objectives. To understand the landscape of the nonfederal governmental public health workforce and to identify replicable methods for future enumerations. Methods. This enumeration of the state and local public health workforce was condu...

» The impact of social welfare support on mental health in Vietnam
08/04/25 20:00 from coronavirus
This study examines the impact of government support on mental health in Vietnam using Vietnam's Households Living Standard Surveys in 2018 and 2020 and a probit estimator. Characteristics of the households and the households' heads are ...

» Advances in Subacute Thyroiditis: Pathogenesis, Diagnosis, and Therapies
08/04/25 20:00 from coronavirus
Subacute thyroiditis (SAT) is an inflammatory thyroid disease that is often associated with viral infections. In particular, SARS-COV-2 and its vaccine were found to cause SAT during the recent COVID-19 pandemic. However, the pathogenesi...

» Associations between different measures of SARS-CoV-2 infection status and subsequent economic inactivity: A pooled analysis of five longitudinal surveys linked to healthcare records
08/04/25 20:00 from coronavirus
CONCLUSIONS: Among people employed pre-pandemic, testing positive for SARS-CoV-2 was not associated with increased economic inactivity, although we could not exclude small effects. Ascertaining infection through healthcare records or sel...

» Barriers and limitations to the development of a telemental health service for workers in Peru- A user-centered approach
08/04/25 20:00 from coronavirus
CONCLUSION: The study advocates for a holistic, user-centred paradigm in telemental health services implementation, addressing both technological aspects and human and systemic elements. Multifaceted challenges inherent in telemental hea...

» Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC
08/04/25 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve and spread, and it remains critical to understand the functional consequences of mutations in dominant viral variants. The recombinant JN.1 subvariant XEC r...

» Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania
08/04/25 20:00 from Covid-19 origins
CONCLUSION: This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing ...

» Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats
08/04/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
It is believed that bats, a natural reservoir host of coronaviruses (CoVs), may coexist with virus for long-term without showing symptoms of diseases. However, this description is mainly from observation on wild-captured bats, but withou...

» Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
08/04/25 20:00 from sars-cov-2 spike protein
Melissa officinalis is a perennial medicinal plant traditionally used for its diverse biological activities, including antiviral properties. This study investigates the antiviral efficacy of various extracts, including water, acetone, al...

» Cardiac symptoms in patients 3-6 months after contracting COVID-19- data from the polish STOP-COVID registry
08/04/25 20:00 from sars-cov-2
CONCLUSION: Cardiological symptoms are common among health issues that patients must face after contracting COVID-19. People with palpitations had more excessive ventricular extrasystoles than patients without these symptoms.

» Altered Circulating Cytokine Profile Among mRNA-Vaccinated Young Adults: A Year-Long Follow-Up Study
08/04/25 20:00 from sars-cov-2 spike protein
CONCLUSIONS: The findings of this study indicated that COVID-19 vaccination resulted in an increase in cytokine levels, which signifies the persistence of the humoral immune response to messenger RNA (mRNA) vaccines. This effect may be a...

» Cross-variant immune shield: computational multiepitope vaccine design against B.617.2 to Omicron sub-lineages in SARS-CoV-2
08/04/25 20:00 from sars-cov-2 spike protein
The COVID-19 pandemic had a profound impact on global health. This study focuses on an in-depth analysis of the structural proteins (Spike (S), Nucleocapsid (N), Membrane (M), and Envelope (E) protein) of SARS-CoV-2 and its variants, aim...

» The impact of insulin requirement on mortality and morbidity in non-diabetic covid-19 patients in the intensive care unit: A retrospective, observational study
08/04/25 20:00 from sars-cov-2
CONCLUSIONS: Insulin requirement in non-diabetic COVID-19 ICU patients is a predictor of 6-month mortality. High-dose corticosteroids exacerbate glycemic dysregulation, increasing insulin needs. SARS-CoV-2-induced beta-cell damage and hy...

» The effect of COVID vaccination timing on the seroprevalence of IgG antibodies: evidence from the Guayas region of Ecuador
08/04/25 20:00 from sars-cov-2 spike protein
CONCLUSION: The results suggest that a significant portion of the study population was already infected with SARS-CoV-2 prior to the vaccination. As expected, seropositivity increased alongside vaccination efforts. We determined that Pfi...

» Perspectives on COVID-19 Vaccination Among Unvaccinated and Under-Vaccinated African American/Black and Latine Frontline Essential Workers: A Qualitative Exploration
08/04/25 20:00 from sars-cov-2
Racial/ethnic disparities in COVID-19 morbidity and mortality are serious in the United States, particularly among African American/Black and Latine (AABL) populations. Staying up-to-date on COVID-19 vaccination is essential for mitigati...

» Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania
08/04/25 20:00 from Sars-Cov-2 origins
CONCLUSION: This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing ...

» Evaluating the Effects of the COVID-19 Pandemic on HIV Testing, Enrollment, ART Use and Mortality in Suriname Using Interrupted Time Series Analysis
08/04/25 20:00 from sars-cov-2
Our study evaluates the changes in HIV testing, new enrollments in the HIV surveillance system, treatment, and mortality of people with HIV during and after the SARS-CoV-2 (COVID-19) pandemic in Suriname. A retrospective population-based...

» The Relationship Between Spiritual Well-Being and Fear of COVID-19 Among Cancer Patients in Turkey
08/04/25 20:00 from coronavirus
This study focuses on the relationship between the faith sub-dimension of spiritual well-being and COVID-19-related fear among cancer patients. The research employs a descriptive, correlational, and cross-sectional approach to understand...

» Optimal Timing of Vaccination: A Narrative Review of Integrating Strategies for COVID-19, Influenza, and Respiratory Syncytial Virus
08/04/25 20:00 from sars-cov-2
Lower respiratory tract infections caused by SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) cause a significant disease burden globally, despite the availability of effective vaccines. Certain populations, such as older adu...

» Emerging Viral Infections (ZIKV, SARS-CoV-2, and MPXV) and Depression: Ketamine and (S, R)-Ketamine as Promising Antidepressants
08/04/25 20:00 from sars-cov-2
Emerging viral pathogens, newly reported or rapidly evolving viruses, are a significant public health concern worldwide. Beyond their characteristic clinical presentations, emerging viruses, such as monkeypox virus (MPXV) and severe acut...

» Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
08/04/25 20:00 from sars-cov-2
Melissa officinalis is a perennial medicinal plant traditionally used for its diverse biological activities, including antiviral properties. This study investigates the antiviral efficacy of various extracts, including water, acetone, al...

» Emerging Viral Infections (ZIKV, SARS-CoV-2, and MPXV) and Depression: Ketamine and (S, R)-Ketamine as Promising Antidepressants
08/04/25 20:00 from coronavirus
Emerging viral pathogens, newly reported or rapidly evolving viruses, are a significant public health concern worldwide. Beyond their characteristic clinical presentations, emerging viruses, such as monkeypox virus (MPXV) and severe acut...

» Antiviral potential of Melissa officinalis extracts against influenza and emerging coronaviruses
08/04/25 20:00 from coronavirus
Melissa officinalis is a perennial medicinal plant traditionally used for its diverse biological activities, including antiviral properties. This study investigates the antiviral efficacy of various extracts, including water, acetone, al...

» Psychological distress in health care workers during the beginning, the middle, and the last part of the COVID-19 pandemic
08/04/25 20:00 from sars-cov-2
The COVID-19 pandemic placed significant psychological strain on healthcare workers. Our study tracked health care workers in the Czech Republic throughout the pandemic to examine the impact of stressors on psychological distress over ti...

» Cardiac symptoms in patients 3-6 months after contracting COVID-19- data from the polish STOP-COVID registry
08/04/25 20:00 from covid-19
CONCLUSION: Cardiological symptoms are common among health issues that patients must face after contracting COVID-19. People with palpitations had more excessive ventricular extrasystoles than patients without these symptoms.

» Psychological distress in health care workers during the beginning, the middle, and the last part of the COVID-19 pandemic
08/04/25 20:00 from coronavirus
The COVID-19 pandemic placed significant psychological strain on healthcare workers. Our study tracked health care workers in the Czech Republic throughout the pandemic to examine the impact of stressors on psychological distress over ti...

» SnO₂NPs as a Nontoxic Antiviral Agent for Designing Protective Masks against Human Coronavirus Infection
08/04/25 20:00 from sars-cov-2
The COVID-19 pandemic has created a need to develop protective textiles that reduce the infection of SARS-CoV-2, mainly via face masks. The key issue in designing protective textiles is the functionalization with antiviral agents. This r...

» SnO₂NPs as a Nontoxic Antiviral Agent for Designing Protective Masks against Human Coronavirus Infection
08/04/25 20:00 from coronavirus
The COVID-19 pandemic has created a need to develop protective textiles that reduce the infection of SARS-CoV-2, mainly via face masks. The key issue in designing protective textiles is the functionalization with antiviral agents. This r...

» Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal (UNIVERSAL) study: a prospective observational cohort study protocol
08/04/25 20:00 from coronavirus
BACKGROUND: Respiratory viral infections (RVIs) are a significant cause of morbidity and hospital admission worldwide. However, the management of most viral infection-associated diseases remains primarily supportive. The recent COVID-19 ...

» Effectiveness of full mRNA vaccinations to prevent COVID-19 among immunocompromised patients receiving tixagevimab-cilgavimab as pre-exposure prophylaxis
08/04/25 20:00 from sars-cov-2
Pre-exposure prophylaxis with monoclonal antibodies (mAbs) offers protection against COVID-19 in immunocompromised patients. To attest full vaccinations, defined by ≥ 3-dose mRNA vaccines, providing additional protection effect on mAbs a...

» Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats
08/04/25 20:00 from coronavirus
It is believed that bats, a natural reservoir host of coronaviruses (CoVs), may coexist with virus for long-term without showing symptoms of diseases. However, this description is mainly from observation on wild-captured bats, but withou...

» Age-Specific Seroprevalence of Measles, Mumps, and Rubella IgG across All Age Groups in Chonburi Province, Thailand after the Coronavirus Disease 2019 Pandemic
08/04/25 20:00 from coronavirus
Thailand's Expanded Program on Immunization revised the timing of the second measles, mumps, and rubella (MMR) vaccine dose to 2.5 years in 2014 and later to 1.5 years in 2020. These adjustments can temporarily reduce vaccine coverage as...

» Impact of pre-Omicron COVID-19 vaccine boosters on the risk of Omicron variant infections: A systematic review and meta-regression
08/04/25 20:00 from sars-cov-2
CONCLUSION: Our findings refute the immune imprinting hypothesis that COVID-19 boosters impair immunity against new SARS-CoV-2 variants and support current recommendations to stay protected through updated booster vaccination once or twi...

» Boosting virus enrichment with macroporous magnetic sorbent based on ketoenamine covalent organic framework
08/04/25 20:00 from coronavirus
Effective surveillance and discovery of emerging and reemerging infectious viruses are crucial for predicting and controlling epidemic outbreaks. However, these efforts are significantly hindered by the low-titer existence of genetically...

» Understanding Infection, Viral Exacerbation and Respiratory Symptoms at Admission-Longitudinal (UNIVERSAL) study: a prospective observational cohort study protocol
08/04/25 20:00 from sars-cov-2
BACKGROUND: Respiratory viral infections (RVIs) are a significant cause of morbidity and hospital admission worldwide. However, the management of most viral infection-associated diseases remains primarily supportive. The recent COVID-19 ...

» Safety Data for Baricitinib Use in Children With Severe SARS-CoV-2 Infection
08/04/25 20:00 from sars-cov-2
CONCLUSIONS: Baricitinib appears safe in children hospitalized for severe COVID-19. Most early baricitinib discontinuation for abnormal laboratory studies was secondary to provider caution.

» Enumerating the State and Local Public Health Workforce During the COVID-19 Response
08/04/25 20:00 from coronavirus
Objectives. To understand the landscape of the nonfederal governmental public health workforce and to identify replicable methods for future enumerations. Methods. This enumeration of the state and local public health workforce was condu...

» Comparative metatranscriptome analysis in gut reveals insignificant host or microbiota changes in SARS-related coronavirus naturally infected bats
08/04/25 20:00 from sars-cov-2
It is believed that bats, a natural reservoir host of coronaviruses (CoVs), may coexist with virus for long-term without showing symptoms of diseases. However, this description is mainly from observation on wild-captured bats, but withou...

» The cost of delivering COVID-19 vaccines in Mozambique: a bottom-up costing study
08/04/25 20:00 from covid-19
CONCLUSIONS: The cost of delivering COVID-19 vaccines in Mozambique was found to be low compared to other countries, due to heavy reliance on existing resources and little additional investment into the program. Findings from this study ...

» Respiratory Syncytial Virus hospitalisation burden in children below 18 years in six European countries (2016-2023) pre- and post-COVID-19 pandemic
08/04/25 20:00 from sars-cov-2
CONCLUSION: Hospital RSV burden in children is significant but currently not fully monitorable. Further efforts to harmonise coding practices both within and across countries would improve the quality of future analyses. Additional data ...

» The impact of social welfare support on mental health in Vietnam
08/04/25 20:00 from coronavirus
This study examines the impact of government support on mental health in Vietnam using Vietnam's Households Living Standard Surveys in 2018 and 2020 and a probit estimator. Characteristics of the households and the households' heads are ...

» The impact of insulin requirement on mortality and morbidity in non-diabetic covid-19 patients in the intensive care unit: A retrospective, observational study
08/04/25 20:00 from covid-19
CONCLUSIONS: Insulin requirement in non-diabetic COVID-19 ICU patients is a predictor of 6-month mortality. High-dose corticosteroids exacerbate glycemic dysregulation, increasing insulin needs. SARS-CoV-2-induced beta-cell damage and hy...

» Advances in Subacute Thyroiditis: Pathogenesis, Diagnosis, and Therapies
08/04/25 20:00 from coronavirus
Subacute thyroiditis (SAT) is an inflammatory thyroid disease that is often associated with viral infections. In particular, SARS-COV-2 and its vaccine were found to cause SAT during the recent COVID-19 pandemic. However, the pathogenesi...

» Online extended focused assessment with sonography for trauma (EFAST) course enhanced knowledge and perceived confidence among medical trainees during the COVID-19 pandemic disaster
08/04/25 20:00 from covid-19
CONCLUSION: The online EFAST course enhanced participants' knowledge and perceived confidence, demonstrating the potential of online clinical education during global crises.

» Associations between different measures of SARS-CoV-2 infection status and subsequent economic inactivity: A pooled analysis of five longitudinal surveys linked to healthcare records
08/04/25 20:00 from coronavirus
CONCLUSIONS: Among people employed pre-pandemic, testing positive for SARS-CoV-2 was not associated with increased economic inactivity, although we could not exclude small effects. Ascertaining infection through healthcare records or sel...

» "There's a lot of unknowns": a thematic analysis of the experiences of young adults with cancer who died during a psychosocial intervention trial
08/04/25 20:00 from covid-19
CONCLUSIONS: YAs who approached end-of-life or saw unexpectedly fast declines in their healthcare trajectory showed many similarities to YAs outside of end-of-life contexts. Some, but not all, participants reflected on goals and challeng...

» Barriers and limitations to the development of a telemental health service for workers in Peru- A user-centered approach
08/04/25 20:00 from coronavirus
CONCLUSION: The study advocates for a holistic, user-centred paradigm in telemental health services implementation, addressing both technological aspects and human and systemic elements. Multifaceted challenges inherent in telemental hea...

» Clinical impact of concurrent autologous adoptive T cells immunotherapy in active COVID-19 infected cancer patients for chemotherapy
08/04/25 20:00 from covid-19
CONCLUSIONS: These data demonstrate the clinical safety profiles while ACT infusions with active COVID-19 infection.The intervention of ACT for cancer patients could generate the benefit for symptom alleviation with improved recovery tim...

» Antibody evasiveness of SARS-CoV-2 subvariants KP.3.1.1 and XEC
08/04/25 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to evolve and spread, and it remains critical to understand the functional consequences of mutations in dominant viral variants. The recombinant JN.1 subvariant XEC r...

» Post COVID-19 among young adults- prevalence and associations with general health, stress, and lifestyle factors
08/04/25 20:00 from covid-19
CONCLUSIONS: Almost 4% of young adults with previous self-reported COVID-19 had ongoing symptoms of PCC three years after the onset of the pandemic. This group reported poorer health and more adverse changes in lifestyle factors than par...

» Enhancing accessibility and equity in utilization of virtual care: Virtual Care @ Your Library pilot project
08/04/25 20:00 from covid-19
CONCLUSIONS: The VC@YL initiative demonstrated how community-based programs can effectively enhance access to virtual care, particularly for individuals facing technological barriers. This pilot project showed strong potential for improv...

» Online Racial Discrimination and College Student Mental Health: Social Support as a Moderator
08/04/25 20:00 from covid-19
Many college students experience racism and discrimination, which negatively impacts their mental health. As COVID-19 has brought about increased reliance on virtual spaces, increased online racial discrimination (ORD) has also become a ...

» Perspectives on COVID-19 Vaccination Among Unvaccinated and Under-Vaccinated African American/Black and Latine Frontline Essential Workers: A Qualitative Exploration
08/04/25 20:00 from covid-19
Racial/ethnic disparities in COVID-19 morbidity and mortality are serious in the United States, particularly among African American/Black and Latine (AABL) populations. Staying up-to-date on COVID-19 vaccination is essential for mitigati...

» Evaluating the Effects of the COVID-19 Pandemic on HIV Testing, Enrollment, ART Use and Mortality in Suriname Using Interrupted Time Series Analysis
08/04/25 20:00 from covid-19
Our study evaluates the changes in HIV testing, new enrollments in the HIV surveillance system, treatment, and mortality of people with HIV during and after the SARS-CoV-2 (COVID-19) pandemic in Suriname. A retrospective population-based...

» Expert consensus on implementing patient-reported outcomes in telehealth: findings from an international Delphi study
08/04/25 20:00 from covid-19
CONCLUSION: The expert consensus achieved provides important insights from an international perspective on how PROs are currently used via telehealth and the needed implementation support to advance their expansion in research and practi...

» The Relationship Between Spiritual Well-Being and Fear of COVID-19 Among Cancer Patients in Turkey
08/04/25 20:00 from covid-19
This study focuses on the relationship between the faith sub-dimension of spiritual well-being and COVID-19-related fear among cancer patients. The research employs a descriptive, correlational, and cross-sectional approach to understand...

» Optimal Timing of Vaccination: A Narrative Review of Integrating Strategies for COVID-19, Influenza, and Respiratory Syncytial Virus
08/04/25 20:00 from covid-19
Lower respiratory tract infections caused by SARS-CoV-2, influenza, and respiratory syncytial virus (RSV) cause a significant disease burden globally, despite the availability of effective vaccines. Certain populations, such as older adu...

» Global Profiles of Positive Youth Development: A Person-Oriented Analysis among Emerging Adults Living in 21 Countries
08/04/25 20:00 from covid-19
Although global research on the 5Cs model of Positive Youth Development (PYD; competence, confidence, connection, character, and caring) has expanded in recent years, there is a lack of understanding about distinct and consistent PYD pro...

» Effectiveness of Group and Individual Counselling Interventions on COVID-19 Vaccination Intention Among Industrial Employees in Romania
08/04/25 20:00 from Coronavirus origins
CONCLUSION: This study highlights the effectiveness of dual interventions involving family doctors and occupational medicine specialists in reducing COVID-19 vaccine hesitancy among industrial workers in Romania. Key factors influencing ...

» Excess Respiratory Hospitalisations Associated with Influenza, Respiratory Syncytial Virus and SARS-CoV-2 in Singapore from 2015 to 2023
07/04/25 20:00 from sars-cov-2
CONCLUSION: The overall burden of influenza has declined after the COVID-19 pandemic and its burden is comparable with SARS-CoV-2. Furthermore, shifts in the timing of peak influenza activity suggest a potential need to review the timing...

» AMULETY: A Python package to embed adaptive immune receptor sequences
07/04/25 20:00 from sars-cov-2
Large language models have been developed to capture relevant features of adaptive immune receptors, each with unique potential applications. However, the diversity in available models presents challenges in accessibility and usability f...

» Quantifying viral pandemic potential from experimental transmission studies
07/04/25 20:00 from sars-cov-2
In the past two decades, two pandemic respiratory viruses (H1N1 and SARS-CoV-2) have emerged via spillover from animal reservoirs. In an effort to avert future pandemics, surveillance studies aimed at identifying zoonotic viruses at high...

» Excess mortality during and after the COVID-19 emergency in Japan: a two-stage interrupted time-series design
07/04/25 20:00 from sars-cov-2
CONCLUSION: Despite initial success in mitigating excess deaths, Japan saw increasing excess mortality as the pandemic progressed, with continued elevation post-emergency. The varying impact across age groups and time highlights the comp...

» Neuropilin-1 as a Neuroinflammatory Entry Factor for SARS-CoV-2 Is Attenuated in Vaccinated COVID-19 Patients: A Case-Control Study
07/04/25 20:00 from sars-cov-2
CONCLUSION: The significant increase in the expression of NRP1 and IL-6 genes in COVID-19 patients, especially in moderate and severe cases, indicates their potential involvement in the progression of the disease, which may serve as biom...

» Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients
07/04/25 20:00 from sars-cov-2
The COVID-19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to...

» Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study
07/04/25 20:00 from sars-cov-2
CONCLUSIONS AND RELEVANCE: Children and adolescents face significantly higher risk of various PASC outcomes after reinfection with SARS-CoV-2. These findings suggest a cumulative risk of PASC and highlight the urgent need for targeted pr...

» Prospective SARS-CoV-2 Booster Vaccination in Immunosuppressant-Treated Systemic Autoimmune Disease Patients in a Randomized Controlled Trial
07/04/25 20:00 from sars-cov-2
CONCLUSION: Additional COVID-19 vaccination is effective and safe in immunosuppressant-treated autoimmune disease patients, regardless of whether MMF/MPA or MTX is withheld. Trial Registration. ClinicalTrials.gov (NCT#05000216).

» Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection
07/04/25 20:00 from sars-cov-2
CONCLUSION: Our results suggest that vaccine-induced antibody responses to SARS-CoV-2 are protective in the gut. Our study also supports previous reports indicating that SARS-CoV-2 vaccines need to be adapted to circulating virus strains...

» Memory B cell proliferation drives differences in neutralising responses between ChAdOx1 and BNT162b2 SARS-CoV-2 vaccines
07/04/25 20:00 from sars-cov-2
INTRODUCTION: Vaccination against COVID-19 has been pivotal in reducing the global burden of the disease. However, Phase III trial results and observational studies underscore differences in efficacy across vaccine technologies and dosin...

» Mutations in ace2 gene modulate cytokine levels and alter immune responses in Mycobacterium tuberculosis and SARS-CoV-2 co-infection: a Cameroonian cohort
07/04/25 20:00 from sars-cov-2
CONCLUSION: These biomarkers may reflect the complex interplay between the two pathogens and their impact on host immune responses and disease progression. This study highlights the critical role of genetic and immunological factors in s...

» A Case Report of a Boy With Clinically Mild Encephalopathy and a Reversible Splenial Lesion Associated With Severe Acute Respiratory Syndrome-Coronavirus 2 Infection
07/04/25 20:00 from sars-cov-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a high frequency of central nervous system abnormalities, particularly acute encephalopathy, in children. We report the case of a nine-year-old boy...

» Investigating the relationship between cycle threshold of SARS-CoV-2 RT-PCR, clinical features, and laboratory data in hospitalized COVID-19 patients in Semnan, Iran
07/04/25 20:00 from sars-cov-2
CONCLUSION: This study provides valuable insights into the association between CT values, clinical characteristics, and laboratory findings in hospitalized COVID-19 patients. The findings underscore the importance of CT values in assessi...

» JUNIPER: Reconstructing Transmission Events from Next-Generation Sequencing Data at Scale
07/04/25 20:00 from sars-cov-2
Transmission reconstruction--the inference of who infects whom in disease outbreaks--offers critical insights into how pathogens spread and provides opportunities for targeted control measures. We developed JUNIPER (Joint Underlying Netw...

» SIV/SARS-CoV-2 co-infection in rhesus macaques impacts viral shedding, host immunity, the microbiome, and viral evolution
07/04/25 20:00 from sars-cov-2
People living with HIV (PLWH) have an increased risk of severe COVID-19, including prolonged viral shedding and emergence of mutations. To investigate the simian immunodeficiency virus (SIV) macaque model for HIV/SARS-CoV-2 co-infection,...

» Effect of the new coronavirus infection COVID-19 on the course and prognosis of tuberculous meningoencephalitis in HIV-infected patients
07/04/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSION: New data were obtained, suggesting correlations between the combination of manifestations of tuberculous meningoencephalitis, HIV, and coronavirus infection with acute toxic-infectious encephalopathy syndrome, as well as the ...

» Excess Respiratory Hospitalisations Associated with Influenza, Respiratory Syncytial Virus and SARS-CoV-2 in Singapore from 2015 to 2023
07/04/25 20:00 from covid-19
CONCLUSION: The overall burden of influenza has declined after the COVID-19 pandemic and its burden is comparable with SARS-CoV-2. Furthermore, shifts in the timing of peak influenza activity suggest a potential need to review the timing...

» Changes in health behaviour of medical students during and after the COVID-19 pandemic-focus on physical activity, screen time, sleep duration, unhealthy foods, alcohol, and tobacco
07/04/25 20:00 from covid-19
INTRODUCTION: The COVID-19 pandemic and the preventive measures led to a change in the health behaviour among the population. Medical students were particularly affected by this. Previous studies primarily focused on few health behaviour...

» Safety of COVID-19 Vaccination in Patients with Rheumatic and Musculoskeletal Diseases: A Cross-sectional Study in Egypt
07/04/25 20:00 from covid-19
CONCLUSIONS: Adverse events following COVID-19 vaccinations in patients with RMD are comparable to controls.

» Retraction notice to "Navigating crisis: The effect of COVID-19 on sports entrepreneurs and service excellence in non-profit organizations" [Heliyon 10 (2024) e32286]
07/04/25 20:00 from covid-19
[This retracts the article DOI: 10.1016/j.heliyon.2024.e32286.].

» New Drug Approvals in China: An International Comparative Analysis, 2019-2023
07/04/25 20:00 from covid-19
CONCLUSION: Despite COVID-19 challenges, China has improved in both the quantity and speed of new drug approvals, narrowing timeline gaps with major markets and enhancing its global pharmaceutical presence.

» Longitudinal recovery trajectories and ventilatory modalities in COVID-19 acute respiratory distress syndrome survivors
07/04/25 20:00 from covid-19
CONCLUSIONS: Delay in intubation implies the worst outcomes; however, patients with NIMV exhibited a slower lung recovery in terms of D (LCO) measurements and more radiological abnormalities compared with HFNC patients. These results sho...

» AMULETY: A Python package to embed adaptive immune receptor sequences
07/04/25 20:00 from covid-19
Large language models have been developed to capture relevant features of adaptive immune receptors, each with unique potential applications. However, the diversity in available models presents challenges in accessibility and usability f...

» Quantifying viral pandemic potential from experimental transmission studies
07/04/25 20:00 from covid-19
In the past two decades, two pandemic respiratory viruses (H1N1 and SARS-CoV-2) have emerged via spillover from animal reservoirs. In an effort to avert future pandemics, surveillance studies aimed at identifying zoonotic viruses at high...

» Gut bacterial lactate stimulates lung epithelial mitochondria and exacerbates acute lung injury
07/04/25 20:00 from covid-19
Acute respiratory distress syndrome (ARDS) is an often fatal critical illness where lung epithelial injury leads to intrapulmonary fluid accumulation. ARDS became widespread during the COVID-19 pandemic, motivating a renewed effort to un...

» Qualitative evaluation of two London Faith and Health Networks: lessons learnt from a model of an interface between health systems and minority communities
07/04/25 20:00 from covid-19
CONCLUSION: This evaluation offers insights into developing partnership models between faith-based organisations and health sectors to foster relationships with underserved communities. These findings provide valuable considerations for ...

» Gender equality in caregiver attendance for children with chronic diseases: a Swedish longitudinal observational study
07/04/25 20:00 from covid-19
CONCLUSION: Mothers attended paediatric outpatient visits more frequently than fathers across all appointment types. The gender gap in attendance remained unchanged after the introduction of video conference visits, while the joint atten...

» Excess mortality during and after the COVID-19 emergency in Japan: a two-stage interrupted time-series design
07/04/25 20:00 from covid-19
CONCLUSION: Despite initial success in mitigating excess deaths, Japan saw increasing excess mortality as the pandemic progressed, with continued elevation post-emergency. The varying impact across age groups and time highlights the comp...

» Oncolytic Virotherapy for Relapsed, IDH-Mutant, Grade 3 Astrocytoma: A New Promising Approach - A Case Report
07/04/25 20:00 from covid-19
CONCLUSION: OV therapy proved to induce significant clinical improvements and radiological NED for this incurable astrocytoma. This promising modality should be evaluated as an adjunct to first-line therapy for inoperable brain tumors.

» The role of social media messages and content creators in shaping COVID-19 vaccination intentions
07/04/25 20:00 from covid-19
CONCLUSION: Our study underscores the potential of integrating the Health Belief Model into social media to help promote health behaviors like the COVID-19 vaccination. Furthermore, our findings offer valuable insights for professionals ...

» Long-Term Effects of the COVID-19 Open Strategy on the Mental Health of Chinese University Students: A Prospective Cohort Study
07/04/25 20:00 from covid-19
CONCLUSIONS: Collectively, the present study indicated that the change of COVID-19 prevention and control policy had more serious negative impacts on the mental health of Chinese university students than the epidemic itself. Thus, streng...

» Longitudinal recovery trajectories and ventilatory modalities in COVID-19 acute respiratory distress syndrome survivors
07/04/25 20:00 from coronavirus
CONCLUSIONS: Delay in intubation implies the worst outcomes; however, patients with NIMV exhibited a slower lung recovery in terms of D (LCO) measurements and more radiological abnormalities compared with HFNC patients. These results sho...

» Post-viral lung diseases: the microbiota as a key player
07/04/25 20:00 from coronavirus
Viral infections of the respiratory tract can lead to chronic lung injury through immunopathological mechanisms that remain unclear. Communities of commensal bacteria colonising the respiratory tract, known as the respiratory tract micro...

» Neuropilin-1 as a Neuroinflammatory Entry Factor for SARS-CoV-2 Is Attenuated in Vaccinated COVID-19 Patients: A Case-Control Study
07/04/25 20:00 from coronavirus
CONCLUSION: The significant increase in the expression of NRP1 and IL-6 genes in COVID-19 patients, especially in moderate and severe cases, indicates their potential involvement in the progression of the disease, which may serve as biom...

» Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients
07/04/25 20:00 from coronavirus
The COVID-19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to...

» Accelerated vaccine process development by orthogonal protein characterization
07/04/25 20:00 from sars-cov-2 spike protein
The COVID-19 pandemic altered the vaccine development paradigm with accelerated timelines from concept through clinical safety and efficacy. Characterization and release assays for vaccine programs were developed under similar time const...

» Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection
07/04/25 20:00 from coronavirus
CONCLUSION: Our results suggest that vaccine-induced antibody responses to SARS-CoV-2 are protective in the gut. Our study also supports previous reports indicating that SARS-CoV-2 vaccines need to be adapted to circulating virus strains...

» Vaccination Coverage Covid-19 and Self-Reported Adverse Post-Vaccination Events in Mbuji-Mayi, DR Congo
07/04/25 20:00 from coronavirus
CONCLUSION: In view of the sub-optimal rate of vaccination coverage, it is evident that the prevailing circumstances have not been immune to the occurrence of adverse events reported by stakeholders following vaccination against the new ...

» CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex
07/04/25 20:00 from sars-cov-2 spike protein
The TMPRSS2 cell surface protease is used by a broad range of respiratory viruses to facilitate entry into target cells. Together with ACE2, TMPRSS2 represents a key factor for SARS-CoV-2 infection, as TMPRSS2 mediates cleavage of viral ...

» A Case Report of a Boy With Clinically Mild Encephalopathy and a Reversible Splenial Lesion Associated With Severe Acute Respiratory Syndrome-Coronavirus 2 Infection
07/04/25 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a high frequency of central nervous system abnormalities, particularly acute encephalopathy, in children. We report the case of a nine-year-old boy...

» Antiviral effect of Bromelain combined with acetylcysteine against SARS-CoV-2 Omicron variant
07/04/25 20:00 from sars-cov-2 spike protein
The recent pandemic represented one of the biggest challenges of modern civilization. SARS-CoV-2 remains an imminent public health threat and currently, there is no effective and greatly affordable treatment for severe COVID-19. Although...

» Neurodevelopmental Outcomes in Preterm Infants at 18 Months of Corrected Age Following Coronavirus Disease 2019 (COVID-19) Pandemic-Related Neonatal Intensive Care Unit (NICU) Care Changes
07/04/25 20:00 from coronavirus
CONCLUSIONS: Preterm infants born during the COVID-19 pandemic exhibited significantly lower cognitive-adaptive and language-social DQs at 18 months corrected age than prepandemic infants. These findings suggest that pandemic-related res...

» Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19
07/04/25 20:00 from coronavirus
Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiated a global pandemic resulting in an estimated 775 million infections with over 7 million deaths, it has become evident that COVID-19 is not solel...

» Impact of Japan's Revised Infectious Disease Control Law on Older Adults' Social Life during the COVID-19 Pandemic
07/04/25 20:00 from coronavirus
CONCLUSION: The increase in socially frail individuals and those with long-term care insurance suggests that, despite the revision of the Infectious Disease Control Law, the connections within the local community that had once weakened d...

» Reconfiguring Vulnerability and Dis/Ability: An Agential Realist Exploration to Disentangle Vulnerability Effects in Austria's COVID-19 Response
07/04/25 20:00 from coronavirus
This article examines how vulnerability emerged, evolved and was contested during Austria's COVID-19 response, by attending to the entangled realities of people with dis/abilities. Using a posthumanist, agential realist lens and a diffra...

» SARS-CoV-2 dynamics in New York City during March 2020-August 2023
07/04/25 20:00 from coronavirus
CONCLUSIONS: This study provides highly detailed epidemiological estimates and identifies key transmission dynamics and drivers of SARS-CoV-2 during its first 3.5 years of circulation in a large urban center (i.e., NYC). These transmissi...

» Accelerated vaccine process development by orthogonal protein characterization
07/04/25 20:00 from coronavirus
The COVID-19 pandemic altered the vaccine development paradigm with accelerated timelines from concept through clinical safety and efficacy. Characterization and release assays for vaccine programs were developed under similar time const...

» CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex
07/04/25 20:00 from coronavirus
The TMPRSS2 cell surface protease is used by a broad range of respiratory viruses to facilitate entry into target cells. Together with ACE2, TMPRSS2 represents a key factor for SARS-CoV-2 infection, as TMPRSS2 mediates cleavage of viral ...

» Antiviral effect of Bromelain combined with acetylcysteine against SARS-CoV-2 Omicron variant
07/04/25 20:00 from coronavirus
The recent pandemic represented one of the biggest challenges of modern civilization. SARS-CoV-2 remains an imminent public health threat and currently, there is no effective and greatly affordable treatment for severe COVID-19. Although...

» Zika virus infection in a non-neural cell host promotes differential expression of proteins associated with neurological conditions
07/04/25 20:00 from sars-cov-2
The Zika Virus (ZIKV) is a Flavivirus that caused a recent outbreak worldwide resulting in different neurological outcomes that are still poorly characterized and understood. Concerning this issue, in vitro and in vivo models are being a...

» Effect of COVID-19 Infection During Pregnancy on the Plasma/Extracellular Vesicles Pro-Inflammatory Cytokine Profile
07/04/25 20:00 from covid-19
CONCLUSION: These findings suggest that COVID-19 infection impacts the pro-inflammatory cytokine profile in the plasma and EVs of South African pregnant women.

» A gold nanoparticle/peptide vaccine designed to induce SARS-CoV-2-specific CD8 T cells: a double-blind, randomized, phase 1 study in Switzerland
07/04/25 20:00 from sars-cov-2
CONCLUSIONS: The favourable safety profile and cellular responses observed support further development of PepGNP-Covid19.

» Spreading of SARS-CoV-2 among adult asylum seekers in refugee community shelters in Lubeck, Germany between 2020 and 2022: a mixed-cohort observational and repeated cross-sectional study
07/04/25 20:00 from sars-cov-2
CONCLUSION: Refugees residing in shared accommodations represent a vulnerable group for SARS-CoV-2 infection and transmission. This increased vulnerability does not diminish over time. Initial doubts regarding vaccination are higher amon...

» Changes in substance use among young Black men who have sex with men during COVID-19 pandemic
07/04/25 20:00 from covid-19
This study examines substance use behaviors and sociodemographic characteristics during the COVID-19 lockdown among young Black men who have sex with men (YBMSM) in California. Using data from the PPOWER² intervention, 132 participants c...

» SARS-CoV-2 epidemiology, kinetics, and evolution: A narrative review
07/04/25 20:00 from sars-cov-2
Since winter 2019, SARS-CoV-2 has emerged, spread, and evolved all around the globe. We explore 4 y of evolutionary epidemiology of this virus, ranging from the applied public health challenges to the more conceptual evolutionary biology...

» Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study
07/04/25 20:00 from covid-19
CONCLUSIONS: We seek to identify biobehavioral predictors to inform treatments that target key factors influencing the severity and course of binge eating. These data, supported solely through federal funding, can inform questions emergi...

» Anti-RBD immunoglobulin levels and their predictive value for SARS-CoV-2 neutralization
07/04/25 20:00 from sars-cov-2
A large number of studies have demonstrated that anti-receptor-binding domain (RBD)-binding antibody titers correlate with SARS-CoV-2 neutralization and protection from the disease. Unlike live virus neutralization assays, antibody-bindi...

» Effect of COVID-19 Infection During Pregnancy on the Plasma/Extracellular Vesicles Pro-Inflammatory Cytokine Profile
07/04/25 20:00 from coronavirus
CONCLUSION: These findings suggest that COVID-19 infection impacts the pro-inflammatory cytokine profile in the plasma and EVs of South African pregnant women.

» Zika virus infection in a non-neural cell host promotes differential expression of proteins associated with neurological conditions
07/04/25 20:00 from covid-19
The Zika Virus (ZIKV) is a Flavivirus that caused a recent outbreak worldwide resulting in different neurological outcomes that are still poorly characterized and understood. Concerning this issue, in vitro and in vivo models are being a...

» Structure and function of an unusual R452-dependent monoclonal antibody against SARS-CoV-2
07/04/25 20:00 from sars-cov-2
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is still a major public health concern worldwide. Currently, SARS-CoV-2 variants have been widely used to de...

» Excess Respiratory Hospitalisations Associated with Influenza, Respiratory Syncytial Virus and SARS-CoV-2 in Singapore from 2015 to 2023
07/04/25 20:00 from sars-cov-2
CONCLUSION: The overall burden of influenza has declined after the COVID-19 pandemic and its burden is comparable with SARS-CoV-2. Furthermore, shifts in the timing of peak influenza activity suggest a potential need to review the timing...

» Survival of critically ill people with COVID-19 and acute kidney injury undergoing hemodialysis in public and private hospitals in Joinville: a cohort study, 2020-2021
07/04/25 20:00 from covid-19
CONCLUSION: Measures implemented during the COVID-19 pandemic may have reduced inequalities between health systems for critically ill patients with acute kidney injury.

» AMULETY: A Python package to embed adaptive immune receptor sequences
07/04/25 20:00 from sars-cov-2
Large language models have been developed to capture relevant features of adaptive immune receptors, each with unique potential applications. However, the diversity in available models presents challenges in accessibility and usability f...

» Serum sST2: key biomarkers in COVID-19 patients with implications for coronary artery disease
07/04/25 20:00 from coronavirus
CONCLUSIONS: Admission serum sST2 levels should be considered in COVID-19 patients with CAD-like symptoms for treatment planning and could serve as a prognostic biomarker for COVID-19 with co-existing CAD in clinical practice.

» Quantifying viral pandemic potential from experimental transmission studies
07/04/25 20:00 from sars-cov-2
In the past two decades, two pandemic respiratory viruses (H1N1 and SARS-CoV-2) have emerged via spillover from animal reservoirs. In an effort to avert future pandemics, surveillance studies aimed at identifying zoonotic viruses at high...

» Reviewed article: Mour EB, Catelano BA, Aguiar FP, Lima H, Franca PHC. Survival of critically ill people with COVID-19 and acute kidney injury undergoing hemodialysis in public and private hospitals in Joinville: a cohort study, 2020-2021. Epidemiol Serv
07/04/25 20:00 from covid-19
No abstract

» Motivation to continue and the value of care work among French Red Cross volunteers and workers during the COVID-19 pandemic: a mixed methods study
07/04/25 20:00 from coronavirus
CONCLUSIONS: Although anxious state and risk perceptions influenced FRC actor motivation to continue during the COVID-19 pandemic, this motivation to continue must be understood in a context of changing values of voluntary and salaried c...

» Excess mortality during and after the COVID-19 emergency in Japan: a two-stage interrupted time-series design
07/04/25 20:00 from sars-cov-2
CONCLUSION: Despite initial success in mitigating excess deaths, Japan saw increasing excess mortality as the pandemic progressed, with continued elevation post-emergency. The varying impact across age groups and time highlights the comp...

» Reviewed article: Mour EB, Catelano BA, Aguiar FP, Lima H, Franca PHC. Survival of critically ill people with COVID-19 and acute kidney injury undergoing hemodialysis in public and private hospitals in Joinville: a cohort study, 2020-2021. Epidemiol Serv
07/04/25 20:00 from covid-19
No abstract

» Neuropilin-1 as a Neuroinflammatory Entry Factor for SARS-CoV-2 Is Attenuated in Vaccinated COVID-19 Patients: A Case-Control Study
07/04/25 20:00 from sars-cov-2
CONCLUSION: The significant increase in the expression of NRP1 and IL-6 genes in COVID-19 patients, especially in moderate and severe cases, indicates their potential involvement in the progression of the disease, which may serve as biom...

» Structure and function of an unusual R452-dependent monoclonal antibody against SARS-CoV-2
07/04/25 20:00 from coronavirus
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is still a major public health concern worldwide. Currently, SARS-CoV-2 variants have been widely used to de...

» Accelerated vaccine process development by orthogonal protein characterization
07/04/25 20:00 from sars-cov-2 spike protein
The COVID-19 pandemic altered the vaccine development paradigm with accelerated timelines from concept through clinical safety and efficacy. Characterization and release assays for vaccine programs were developed under similar time const...

» Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients
07/04/25 20:00 from sars-cov-2
The COVID-19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to...

» Nationwide Assessment of Pulmonary Function Testing Practices and Safety Compliance During the COVID-19 Pandemic
07/04/25 20:00 from coronavirus
CONCLUSION: The survey found that pulmonologists have acted quickly and made moderate success in making preparations in PFT labs for the COVID-19 pandemic. Nevertheless, safer practice in PFT units still needs to be implemented.

» Peripheral promises: expectations, coalitions and covid-19 vaccines in Argentina
07/04/25 20:00 from covid-19
Covid-19 vaccines have shown great promise in addressing the health crisis, including in the global periphery. This work analyzes the construction and mobilization of technoscientific promises to ensure vaccine access in Argentina. Based...

» Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study
07/04/25 20:00 from sars-cov-2
CONCLUSIONS AND RELEVANCE: Children and adolescents face significantly higher risk of various PASC outcomes after reinfection with SARS-CoV-2. These findings suggest a cumulative risk of PASC and highlight the urgent need for targeted pr...

» Longitudinal recovery trajectories and ventilatory modalities in COVID-19 acute respiratory distress syndrome survivors
07/04/25 20:00 from coronavirus
CONCLUSIONS: Delay in intubation implies the worst outcomes; however, patients with NIMV exhibited a slower lung recovery in terms of D (LCO) measurements and more radiological abnormalities compared with HFNC patients. These results sho...

» Prospective SARS-CoV-2 Booster Vaccination in Immunosuppressant-Treated Systemic Autoimmune Disease Patients in a Randomized Controlled Trial
07/04/25 20:00 from sars-cov-2
CONCLUSION: Additional COVID-19 vaccination is effective and safe in immunosuppressant-treated autoimmune disease patients, regardless of whether MMF/MPA or MTX is withheld. Trial Registration. ClinicalTrials.gov (NCT#05000216).

» Post-viral lung diseases: the microbiota as a key player
07/04/25 20:00 from coronavirus
Viral infections of the respiratory tract can lead to chronic lung injury through immunopathological mechanisms that remain unclear. Communities of commensal bacteria colonising the respiratory tract, known as the respiratory tract micro...

» Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection
07/04/25 20:00 from sars-cov-2
CONCLUSION: Our results suggest that vaccine-induced antibody responses to SARS-CoV-2 are protective in the gut. Our study also supports previous reports indicating that SARS-CoV-2 vaccines need to be adapted to circulating virus strains...

» Neuropilin-1 as a Neuroinflammatory Entry Factor for SARS-CoV-2 Is Attenuated in Vaccinated COVID-19 Patients: A Case-Control Study
07/04/25 20:00 from coronavirus
CONCLUSION: The significant increase in the expression of NRP1 and IL-6 genes in COVID-19 patients, especially in moderate and severe cases, indicates their potential involvement in the progression of the disease, which may serve as biom...

» Temporal and spatial trends of accidents with venomous animal in Brazil before and during the COVID-19 pandemic: a population-based ecological study
07/04/25 20:00 from covid-19
CONCLUSION: There was a stable trend in accidents involving venomous animals from 2020 to 2022 in Brazil. The spatial distribution of cases was heterogeneous for both periods studied.

» Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients
07/04/25 20:00 from coronavirus
The COVID-19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to...

» Ruxolitinib for Emergency Treatment of COVID-19-Associated Cytokine Storm: Findings From an Expanded Access Study
07/04/25 20:00 from covid-19
CONCLUSIONS: Overall, some hospitalized patients with COVID-19-associated cytokine storm who received ruxolitinib experienced clinical status improvement; ruxolitinib was well tolerated.

» Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection
07/04/25 20:00 from coronavirus
CONCLUSION: Our results suggest that vaccine-induced antibody responses to SARS-CoV-2 are protective in the gut. Our study also supports previous reports indicating that SARS-CoV-2 vaccines need to be adapted to circulating virus strains...

» CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex
07/04/25 20:00 from sars-cov-2 spike protein
The TMPRSS2 cell surface protease is used by a broad range of respiratory viruses to facilitate entry into target cells. Together with ACE2, TMPRSS2 represents a key factor for SARS-CoV-2 infection, as TMPRSS2 mediates cleavage of viral ...

» Masterful ecofriendly maintainable spectrophotometric techniques for considering indacaterol acetate and mometasone furoate: full evaluation and comparison of their greenness, whiteness, and blueness profiles
07/04/25 20:00 from covid-19
People of all ages may suffer from asthma. According to recent research, those who have poorly controlled asthma may be more susceptible to hospitalization and severe symptoms from any respiratory infection, particularly severe ones like...

» Vaccination Coverage Covid-19 and Self-Reported Adverse Post-Vaccination Events in Mbuji-Mayi, DR Congo
07/04/25 20:00 from coronavirus
CONCLUSION: In view of the sub-optimal rate of vaccination coverage, it is evident that the prevailing circumstances have not been immune to the occurrence of adverse events reported by stakeholders following vaccination against the new ...

» Antiviral effect of Bromelain combined with acetylcysteine against SARS-CoV-2 Omicron variant
07/04/25 20:00 from sars-cov-2 spike protein
The recent pandemic represented one of the biggest challenges of modern civilization. SARS-CoV-2 remains an imminent public health threat and currently, there is no effective and greatly affordable treatment for severe COVID-19. Although...

» A Case Report of a Boy With Clinically Mild Encephalopathy and a Reversible Splenial Lesion Associated With Severe Acute Respiratory Syndrome-Coronavirus 2 Infection
07/04/25 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a high frequency of central nervous system abnormalities, particularly acute encephalopathy, in children. We report the case of a nine-year-old boy...

» Moran's I and Geary's C: investigation of the effects of spatial weight matrices for assessing the distribution of infectious diseases
07/04/25 20:00 from covid-19
The COVID-19 outbreak has precipitated severe occurrences on a global scale. Hence, spatial analysis is crucial in determining the relationships and patterns of geospatial data. Moran's I and Geary's C are prominent methodologies used to...

» Neurodevelopmental Outcomes in Preterm Infants at 18 Months of Corrected Age Following Coronavirus Disease 2019 (COVID-19) Pandemic-Related Neonatal Intensive Care Unit (NICU) Care Changes
07/04/25 20:00 from coronavirus
CONCLUSIONS: Preterm infants born during the COVID-19 pandemic exhibited significantly lower cognitive-adaptive and language-social DQs at 18 months corrected age than prepandemic infants. These findings suggest that pandemic-related res...

» Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19
07/04/25 20:00 from coronavirus
Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiated a global pandemic resulting in an estimated 775 million infections with over 7 million deaths, it has become evident that COVID-19 is not solel...

» Characterization of COVID-19-Associated Candidemia Among Burn Patients
07/04/25 20:00 from covid-19
CONCLUSION: Our findings indicate that colonization may act as an important prognostic factor prior to the onset of candidemia. In addition, prolonged hospitalization, catheter use, and concurrent COVID-19 infection were identified as ke...

» Impact of Japan's Revised Infectious Disease Control Law on Older Adults' Social Life during the COVID-19 Pandemic
07/04/25 20:00 from coronavirus
CONCLUSION: The increase in socially frail individuals and those with long-term care insurance suggests that, despite the revision of the Infectious Disease Control Law, the connections within the local community that had once weakened d...

» Changes and trends in mortality, disability-adjusted life years, life expectancy, and healthy life expectancy in China from 1990 to 2021: a secondary analysis of the global burden of disease 2021
07/04/25 20:00 from covid-19
CONCLUSION: Effective policy implementation and technological advancements could play a crucial role in alleviating disease burdens associated with aging in China, thereby reducing the country's all-cause mortality rate and enhancing the...

» Fgl2 regulates FcγRIIB+CD8+ T cell responses during infection
07/04/25 20:00 from covid-19
While the inhibitory receptor FcγRIIB has been shown to be upregulated on activated CD8+ T cells in both mice and humans, its effect on T cell fate during infection has not been fully elucidated. We identified an increase in FcγRIIB-expr...

» Effect of the new coronavirus infection COVID-19 on the course and prognosis of tuberculous meningoencephalitis in HIV-infected patients
07/04/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSION: New data were obtained, suggesting correlations between the combination of manifestations of tuberculous meningoencephalitis, HIV, and coronavirus infection with acute toxic-infectious encephalopathy syndrome, as well as the ...

» Zika virus infection in a non-neural cell host promotes differential expression of proteins associated with neurological conditions
07/04/25 20:00 from sars-cov-2
The Zika Virus (ZIKV) is a Flavivirus that caused a recent outbreak worldwide resulting in different neurological outcomes that are still poorly characterized and understood. Concerning this issue, in vitro and in vivo models are being a...

» Effect of the new coronavirus infection COVID-19 on the course and prognosis of tuberculous meningoencephalitis in HIV-infected patients
07/04/25 20:00 from SARS-CoV-2 and Sars-Cov comparisons
CONCLUSION: New data were obtained, suggesting correlations between the combination of manifestations of tuberculous meningoencephalitis, HIV, and coronavirus infection with acute toxic-infectious encephalopathy syndrome, as well as the ...

» Effect of COVID-19 Infection During Pregnancy on the Plasma/Extracellular Vesicles Pro-Inflammatory Cytokine Profile
07/04/25 20:00 from covid-19
CONCLUSION: These findings suggest that COVID-19 infection impacts the pro-inflammatory cytokine profile in the plasma and EVs of South African pregnant women.

» A gold nanoparticle/peptide vaccine designed to induce SARS-CoV-2-specific CD8 T cells: a double-blind, randomized, phase 1 study in Switzerland
07/04/25 20:00 from sars-cov-2
CONCLUSIONS: The favourable safety profile and cellular responses observed support further development of PepGNP-Covid19.

» Changes in substance use among young Black men who have sex with men during COVID-19 pandemic
07/04/25 20:00 from covid-19
This study examines substance use behaviors and sociodemographic characteristics during the COVID-19 lockdown among young Black men who have sex with men (YBMSM) in California. Using data from the PPOWER² intervention, 132 participants c...

» Accelerated vaccine process development by orthogonal protein characterization
07/04/25 20:00 from sars-cov-2 spike protein
The COVID-19 pandemic altered the vaccine development paradigm with accelerated timelines from concept through clinical safety and efficacy. Characterization and release assays for vaccine programs were developed under similar time const...

» Effect of COVID-19 Infection During Pregnancy on the Plasma/Extracellular Vesicles Pro-Inflammatory Cytokine Profile
07/04/25 20:00 from coronavirus
CONCLUSION: These findings suggest that COVID-19 infection impacts the pro-inflammatory cytokine profile in the plasma and EVs of South African pregnant women.

» Spreading of SARS-CoV-2 among adult asylum seekers in refugee community shelters in Lubeck, Germany between 2020 and 2022: a mixed-cohort observational and repeated cross-sectional study
07/04/25 20:00 from sars-cov-2
CONCLUSION: Refugees residing in shared accommodations represent a vulnerable group for SARS-CoV-2 infection and transmission. This increased vulnerability does not diminish over time. Initial doubts regarding vaccination are higher amon...

» CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex
07/04/25 20:00 from sars-cov-2 spike protein
The TMPRSS2 cell surface protease is used by a broad range of respiratory viruses to facilitate entry into target cells. Together with ACE2, TMPRSS2 represents a key factor for SARS-CoV-2 infection, as TMPRSS2 mediates cleavage of viral ...

» Examining Weight Suppression, Leptin Levels, Glucagon-Like Peptide 1 Response, and Reward-Related Constructs in Severity and Maintenance of Bulimic Syndromes: Protocol and Sample Characteristics for a Cross-Sectional and Longitudinal Study
07/04/25 20:00 from covid-19
CONCLUSIONS: We seek to identify biobehavioral predictors to inform treatments that target key factors influencing the severity and course of binge eating. These data, supported solely through federal funding, can inform questions emergi...

» SARS-CoV-2 epidemiology, kinetics, and evolution: A narrative review
07/04/25 20:00 from sars-cov-2
Since winter 2019, SARS-CoV-2 has emerged, spread, and evolved all around the globe. We explore 4 y of evolutionary epidemiology of this virus, ranging from the applied public health challenges to the more conceptual evolutionary biology...

» Serum sST2: key biomarkers in COVID-19 patients with implications for coronary artery disease
07/04/25 20:00 from coronavirus
CONCLUSIONS: Admission serum sST2 levels should be considered in COVID-19 patients with CAD-like symptoms for treatment planning and could serve as a prognostic biomarker for COVID-19 with co-existing CAD in clinical practice.

» Anti-RBD immunoglobulin levels and their predictive value for SARS-CoV-2 neutralization
07/04/25 20:00 from sars-cov-2
A large number of studies have demonstrated that anti-receptor-binding domain (RBD)-binding antibody titers correlate with SARS-CoV-2 neutralization and protection from the disease. Unlike live virus neutralization assays, antibody-bindi...

» Antiviral effect of Bromelain combined with acetylcysteine against SARS-CoV-2 Omicron variant
07/04/25 20:00 from sars-cov-2 spike protein
The recent pandemic represented one of the biggest challenges of modern civilization. SARS-CoV-2 remains an imminent public health threat and currently, there is no effective and greatly affordable treatment for severe COVID-19. Although...

» Zika virus infection in a non-neural cell host promotes differential expression of proteins associated with neurological conditions
07/04/25 20:00 from covid-19
The Zika Virus (ZIKV) is a Flavivirus that caused a recent outbreak worldwide resulting in different neurological outcomes that are still poorly characterized and understood. Concerning this issue, in vitro and in vivo models are being a...

» Motivation to continue and the value of care work among French Red Cross volunteers and workers during the COVID-19 pandemic: a mixed methods study
07/04/25 20:00 from coronavirus
CONCLUSIONS: Although anxious state and risk perceptions influenced FRC actor motivation to continue during the COVID-19 pandemic, this motivation to continue must be understood in a context of changing values of voluntary and salaried c...

» Structure and function of an unusual R452-dependent monoclonal antibody against SARS-CoV-2
07/04/25 20:00 from sars-cov-2
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is still a major public health concern worldwide. Currently, SARS-CoV-2 variants have been widely used to de...

» Survival of critically ill people with COVID-19 and acute kidney injury undergoing hemodialysis in public and private hospitals in Joinville: a cohort study, 2020-2021
07/04/25 20:00 from covid-19
CONCLUSION: Measures implemented during the COVID-19 pandemic may have reduced inequalities between health systems for critically ill patients with acute kidney injury.

» Structure and function of an unusual R452-dependent monoclonal antibody against SARS-CoV-2
07/04/25 20:00 from coronavirus
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is still a major public health concern worldwide. Currently, SARS-CoV-2 variants have been widely used to de...

» Excess Respiratory Hospitalisations Associated with Influenza, Respiratory Syncytial Virus and SARS-CoV-2 in Singapore from 2015 to 2023
07/04/25 20:00 from sars-cov-2
CONCLUSION: The overall burden of influenza has declined after the COVID-19 pandemic and its burden is comparable with SARS-CoV-2. Furthermore, shifts in the timing of peak influenza activity suggest a potential need to review the timing...

» Reviewed article: Mour EB, Catelano BA, Aguiar FP, Lima H, Franca PHC. Survival of critically ill people with COVID-19 and acute kidney injury undergoing hemodialysis in public and private hospitals in Joinville: a cohort study, 2020-2021. Epidemiol Serv
07/04/25 20:00 from covid-19
No abstract

» Nationwide Assessment of Pulmonary Function Testing Practices and Safety Compliance During the COVID-19 Pandemic
07/04/25 20:00 from coronavirus
CONCLUSION: The survey found that pulmonologists have acted quickly and made moderate success in making preparations in PFT labs for the COVID-19 pandemic. Nevertheless, safer practice in PFT units still needs to be implemented.

» Reviewed article: Mour EB, Catelano BA, Aguiar FP, Lima H, Franca PHC. Survival of critically ill people with COVID-19 and acute kidney injury undergoing hemodialysis in public and private hospitals in Joinville: a cohort study, 2020-2021. Epidemiol Serv
07/04/25 20:00 from covid-19
No abstract

» AMULETY: A Python package to embed adaptive immune receptor sequences
07/04/25 20:00 from sars-cov-2
Large language models have been developed to capture relevant features of adaptive immune receptors, each with unique potential applications. However, the diversity in available models presents challenges in accessibility and usability f...

» Longitudinal recovery trajectories and ventilatory modalities in COVID-19 acute respiratory distress syndrome survivors
07/04/25 20:00 from coronavirus
CONCLUSIONS: Delay in intubation implies the worst outcomes; however, patients with NIMV exhibited a slower lung recovery in terms of D (LCO) measurements and more radiological abnormalities compared with HFNC patients. These results sho...

» Peripheral promises: expectations, coalitions and covid-19 vaccines in Argentina
07/04/25 20:00 from covid-19
Covid-19 vaccines have shown great promise in addressing the health crisis, including in the global periphery. This work analyzes the construction and mobilization of technoscientific promises to ensure vaccine access in Argentina. Based...

» Quantifying viral pandemic potential from experimental transmission studies
07/04/25 20:00 from sars-cov-2
In the past two decades, two pandemic respiratory viruses (H1N1 and SARS-CoV-2) have emerged via spillover from animal reservoirs. In an effort to avert future pandemics, surveillance studies aimed at identifying zoonotic viruses at high...

» Post-viral lung diseases: the microbiota as a key player
07/04/25 20:00 from coronavirus
Viral infections of the respiratory tract can lead to chronic lung injury through immunopathological mechanisms that remain unclear. Communities of commensal bacteria colonising the respiratory tract, known as the respiratory tract micro...

» Excess mortality during and after the COVID-19 emergency in Japan: a two-stage interrupted time-series design
07/04/25 20:00 from sars-cov-2
CONCLUSION: Despite initial success in mitigating excess deaths, Japan saw increasing excess mortality as the pandemic progressed, with continued elevation post-emergency. The varying impact across age groups and time highlights the comp...

» Neuropilin-1 as a Neuroinflammatory Entry Factor for SARS-CoV-2 Is Attenuated in Vaccinated COVID-19 Patients: A Case-Control Study
07/04/25 20:00 from coronavirus
CONCLUSION: The significant increase in the expression of NRP1 and IL-6 genes in COVID-19 patients, especially in moderate and severe cases, indicates their potential involvement in the progression of the disease, which may serve as biom...

» Temporal and spatial trends of accidents with venomous animal in Brazil before and during the COVID-19 pandemic: a population-based ecological study
07/04/25 20:00 from covid-19
CONCLUSION: There was a stable trend in accidents involving venomous animals from 2020 to 2022 in Brazil. The spatial distribution of cases was heterogeneous for both periods studied.

» Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients
07/04/25 20:00 from coronavirus
The COVID-19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to...

» Neuropilin-1 as a Neuroinflammatory Entry Factor for SARS-CoV-2 Is Attenuated in Vaccinated COVID-19 Patients: A Case-Control Study
07/04/25 20:00 from sars-cov-2
CONCLUSION: The significant increase in the expression of NRP1 and IL-6 genes in COVID-19 patients, especially in moderate and severe cases, indicates their potential involvement in the progression of the disease, which may serve as biom...

» Ruxolitinib for Emergency Treatment of COVID-19-Associated Cytokine Storm: Findings From an Expanded Access Study
07/04/25 20:00 from covid-19
CONCLUSIONS: Overall, some hospitalized patients with COVID-19-associated cytokine storm who received ruxolitinib experienced clinical status improvement; ruxolitinib was well tolerated.

» Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection
07/04/25 20:00 from coronavirus
CONCLUSION: Our results suggest that vaccine-induced antibody responses to SARS-CoV-2 are protective in the gut. Our study also supports previous reports indicating that SARS-CoV-2 vaccines need to be adapted to circulating virus strains...

» Masterful ecofriendly maintainable spectrophotometric techniques for considering indacaterol acetate and mometasone furoate: full evaluation and comparison of their greenness, whiteness, and blueness profiles
07/04/25 20:00 from covid-19
People of all ages may suffer from asthma. According to recent research, those who have poorly controlled asthma may be more susceptible to hospitalization and severe symptoms from any respiratory infection, particularly severe ones like...

» Antivirals in COVID-19: A Focus on Pediatric Cardiac Patients
07/04/25 20:00 from sars-cov-2
The COVID-19 pandemic created an unprecedented public health crisis, driven by its rapid global spread and the urgent need for worldwide collaborative interventions to contain it. This urgency spurred the search for therapeutic agents to...

» Vaccination Coverage Covid-19 and Self-Reported Adverse Post-Vaccination Events in Mbuji-Mayi, DR Congo
07/04/25 20:00 from coronavirus
CONCLUSION: In view of the sub-optimal rate of vaccination coverage, it is evident that the prevailing circumstances have not been immune to the occurrence of adverse events reported by stakeholders following vaccination against the new ...

» Moran's I and Geary's C: investigation of the effects of spatial weight matrices for assessing the distribution of infectious diseases
07/04/25 20:00 from covid-19
The COVID-19 outbreak has precipitated severe occurrences on a global scale. Hence, spatial analysis is crucial in determining the relationships and patterns of geospatial data. Moran's I and Geary's C are prominent methodologies used to...

» A Case Report of a Boy With Clinically Mild Encephalopathy and a Reversible Splenial Lesion Associated With Severe Acute Respiratory Syndrome-Coronavirus 2 Infection
07/04/25 20:00 from coronavirus
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with a high frequency of central nervous system abnormalities, particularly acute encephalopathy, in children. We report the case of a nine-year-old boy...

» Reinfection with SARS-CoV-2 in the Omicron Era is Associated with Increased Risk of Post-Acute Sequelae of SARS-CoV-2 Infection: A RECOVER-EHR Cohort Study
07/04/25 20:00 from sars-cov-2
CONCLUSIONS AND RELEVANCE: Children and adolescents face significantly higher risk of various PASC outcomes after reinfection with SARS-CoV-2. These findings suggest a cumulative risk of PASC and highlight the urgent need for targeted pr...

» Neurodevelopmental Outcomes in Preterm Infants at 18 Months of Corrected Age Following Coronavirus Disease 2019 (COVID-19) Pandemic-Related Neonatal Intensive Care Unit (NICU) Care Changes
07/04/25 20:00 from coronavirus
CONCLUSIONS: Preterm infants born during the COVID-19 pandemic exhibited significantly lower cognitive-adaptive and language-social DQs at 18 months corrected age than prepandemic infants. These findings suggest that pandemic-related res...

» Prospective SARS-CoV-2 Booster Vaccination in Immunosuppressant-Treated Systemic Autoimmune Disease Patients in a Randomized Controlled Trial
07/04/25 20:00 from sars-cov-2
CONCLUSION: Additional COVID-19 vaccination is effective and safe in immunosuppressant-treated autoimmune disease patients, regardless of whether MMF/MPA or MTX is withheld. Trial Registration. ClinicalTrials.gov (NCT#05000216).

» Characterization of COVID-19-Associated Candidemia Among Burn Patients
07/04/25 20:00 from covid-19
CONCLUSION: Our findings indicate that colonization may act as an important prognostic factor prior to the onset of candidemia. In addition, prolonged hospitalization, catheter use, and concurrent COVID-19 infection were identified as ke...

» Translating animal models of SARS-CoV-2 infection to vascular, neurological and gastrointestinal manifestations of COVID-19
07/04/25 20:00 from coronavirus
Since the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) initiated a global pandemic resulting in an estimated 775 million infections with over 7 million deaths, it has become evident that COVID-19 is not solel...

» Strain- and vaccine-specific effects of serum antibodies in the protection of intestinal SARS-CoV-2 infection
07/04/25 20:00 from sars-cov-2
CONCLUSION: Our results suggest that vaccine-induced antibody responses to SARS-CoV-2 are protective in the gut. Our study also supports previous reports indicating that SARS-CoV-2 vaccines need to be adapted to circulating virus strains...

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